منابع مشابه
Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis.
Inflammation-induced cholestasis (IIC) is a frequently occurring phenomenon. A central role in its pathogenesis is played by nuclear receptors (NRs). These ligand-activated transcription factors not only regulate basal expression of hepatobiliary transport systems, but also mediate adaptive responses to inflammation and possess anti-inflammatory characteristics. The latter two functions may be ...
متن کاملDrug-induced cholestasis: case report
Background: Clopidogrel is an effective anti-platelet drug that is commonly prescribed for patients with atherosclerotic coronary and peripheral vascular diseases, especially after angioplasty and coronary artery bypass graft surgery. Even though this drug seems safe, there are case reports of important side effects with its use. Case Presentation: The patient was 67 years old male admitted wi...
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Jaundice and hepatic dysfunction frequently accompany a variety of bacterial infections. The relationship between sepsis and jaundice, particularly in a pediatric population, was reported as early as 1837.1 Jaundice may result either directly from bacterial products or as a consequence of the host’s response to infection. Frequently, both factors contribute to the development of jaundice. In ad...
متن کاملDrug‐induced cholestasis
Cholestatic drug-induced liver injury (DILI) can be a diagnostic challenge due to a large differential diagnosis, variability in clinical presentation, and lack of serologic biomarkers associated with this condition. The clinical presentation of drug-induced cholestasis includes bland cholestasis, cholestatic hepatitis, secondary sclerosing cholangitis, and vanishing bile duct syndrome. The ass...
متن کاملGabapentin induced cholestasis.
well known and well regarded among the people in this part of Sweden, where it has been running since 1985, and the great willingness to give consent to genetic research emphasises the importance of close researcher-participant interaction. We conclude that (a) it is feasible to obtain individual consent for genetic research many years after blood was donated; (b) people’s readiness to contribu...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 1999
ISSN: 0815-9319,1440-1746
DOI: 10.1046/j.1440-1746.1999.01982.x